• AOD-9604 VIAL (5MG)
  • AOD-9604 VIAL (5MG)
Research-grade

AOD-9604 VIAL (5MG)

Icon 99,9 % pure
Icon No heavy metals
Icon USP-Quality

Brain Icon Standardized lyophilized format
Blitz Icon Sterile, sealed research vial
Microscope Icon Documented lot & traceability
Security Icon For laboratory research use only
BAC WATER 10 mL
FREE
BAC WATER 10 mL
2x
BAC WATER 10 mL

$15.00

FREE
BAC WATER 10 mL
FREE
BAC WATER 10 mL
3x
BAC WATER 10 mL

$15.00

FREE

    Description

    MB1® AOD-9604 is a high-purity peptide presented in a 5mg lyophilized powder format, intended exclusively for laboratory research and development purposes. With a verified purity of 99% or higher, each batch is rigorously tested using both HPLC and LC-MS analytical methods. Packaged in a sterile, sealed vial, AOD-9604 is designed to maintain maximum stability, consistency, and integrity during research applications.

    MB1 Labs Peptides

    Modified HGH Fragment

    Fat Metabolism Without IGF-1: The Isolated Lipolytic Domain

    AOD-9604 is a modified 16-amino-acid C-terminal fragment of human growth hormone (Tyr-hGH 177-191) with a stabilizing disulfide bridge. Unlike full HGH, AOD-9604 retains only the lipolytic domain — stimulating fat breakdown and inhibiting lipogenesis without affecting IGF-1 levels or glucose tolerance. Phase 2b trials in 300 obese individuals showed the peptide tripled weight loss compared to placebo with a safety profile indistinguishable from placebo.

    • 16-amino-acid fragment: Tyr-hGH 177-191 with disulfide bridge
    • Stimulates lipolysis (fat breakdown)
    • Inhibits lipogenesis (fat storage)
    • No meaningful IGF-1 elevation
    • Placebo-like safety profile in human trials
    Multi-Pathway Mechanism

    How AOD-9604 Achieves Fat Loss Without HGH Side Effects

    AOD-9604 was originally thought to work exclusively via β3-adrenergic receptors on white adipose tissue. However, research in β3-AR knockout mice revealed fat loss still occurs — indicating at least two distinct mechanisms. The secondary pathway may involve direct induction of apoptosis in white fat cells. This dual-mechanism approach explains the peptide's robust efficacy while maintaining metabolic safety — no antibody formation, no insulin resistance, no glucose intolerance.

    • β3-adrenergic receptor activation (shifts fat to "usage mode")
    • Secondary pathway: Possible adipocyte apoptosis induction
    • Works even in β3-AR knockout models
    • No antibody formation (structural similarity to HGH)
    • No insulin resistance or glucose intolerance
    Expanding Research Applications

    From Obesity to Joint Repair and Cardiovascular Protection

    Beyond fat metabolism, AOD-9604 research has expanded into unexpected territories. Intra-articular injections show synergistic effects with hyaluronic acid in osteoarthritis models — improving pain, disability, and cartilage structure at both gross and microscopic levels. Cardiovascular research suggests the peptide may improve metabolic markers beyond its obesity effects, similar to pioglitazone and acipimox — potentially through the same secondary pathway that enables β3-AR-independent fat loss.

    • Obesity: Tripled weight loss vs placebo in Phase 2b
    • Osteoarthritis: Synergy with hyaluronic acid, cartilage improvement
    • Cardiovascular: Metabolic benefits beyond fat reduction
    • Steady weight loss rate (no resistance development)
    • Novel cartilage growth pathway research

    MB1 LABS VS TYPICAL PEPTIDE SELLER

    Clear specs & documentation per product

    Minimal product information

    Standardized vial format and fill amount

    Mixed packaging, unclear content

    Practical storage & handling guidance

    Practical storage & handling guidance

    Lot number on every vial for traceability

    Hard to trace individual batches

    Fast, helpful support for docs & orders

    Slow or generic customer support

    Everything You Need to Know!

    Frequently Asked Questions

    A sterile, sealed vial containing a defined amount of lyophilized peptide, labeled with product name and lot number.

    Yes. A COA is available for every lot and can be requested from our support team.

    Each batch is analyzed using established methods (e.g. HPLC, MS) to confirm identity and purity as stated on the COA.

    Store unopened vials in a refrigerator (2–8 °C), protected from light and moisture, unless otherwise indicated on the product label.

    No. All MB1 Labs products are supplied strictly as laboratory reagents for research use only and are not intended for human or veterinary use, diagnostics, or therapy.

    Related products
    • Third-party tested

      Independent analytical testing to verify identity and purity of each batch.

    • COAs FOR EVERY LOT

      Comprehensive Certificates of Analysis available for all released batches.

    • RESEARCH-ONLY USE

      Supplied strictly as laboratory reagents – not for human or veterinary use.

    • CONTROLLED HANDLING

      Standardized storage and handling to help preserve compound integrity.