MB1 Labs Peptides

Melanocortin Receptor Agonist

A Synthetic α-MSH Analog for Pigmentation Research

Melanotan II is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). Developed in the 1980s, this compound targets melanocortin receptors — particularly MC1R and MC4R — making it a valuable tool for researchers investigating pigmentation mechanisms, appetite regulation, and neuroendocrine signaling pathways.

  • Synthetic analog of α-melanocyte-stimulating hormone
  • Targets MC1R (pigmentation) and MC4R (neuroendocrine)
  • Cyclic heptapeptide structure for enhanced stability
  • Developed for melanocortin receptor research
  • High purity for reliable experimental outcomes
Melanocortin Signaling

How Melanotan II Activates Pigmentation Pathways

Melanotan II binds to melanocortin receptors on melanocytes, triggering intracellular signaling cascades that stimulate melanin synthesis and distribution. Through MC1R activation, it promotes eumelanin production — the dark pigment responsible for skin and hair coloration. Its activity at MC4R has also made it relevant for appetite regulation and neuroendocrine research.

  • Activates MC1R on melanocytes for melanin production
  • Stimulates eumelanin synthesis (dark pigment)
  • MC4R activity relevant to appetite and energy studies
  • Cyclic structure provides receptor binding stability
  • Effects accumulate over repeated administration
Research Applications

From Pigmentation Studies to Neuroendocrine Research

Melanotan II has become a key compound for researchers exploring the melanocortin system — one of the body's most important regulatory networks. Its multi-receptor activity makes it valuable for studies spanning pigmentation biology, appetite and feeding behavior, sexual function pathways, and broader neuroendocrine signaling mechanisms.

  • Pigmentation and melanogenesis studies
  • Melanocortin receptor characterization
  • Appetite regulation and feeding behavior research
  • Neuroendocrine signaling pathway exploration
  • MC1R and MC4R selectivity studies
  • Photoprotection mechanism research

MB1 LABS VS TYPICAL PEPTIDE SELLER

Clear specs & documentation per product

Minimal product information

Standardized vial format and fill amount

Mixed packaging, unclear content

Practical storage & handling guidance

Practical storage & handling guidance

Lot number on every vial for traceability

Hard to trace individual batches

Fast, helpful support for docs & orders

Slow or generic customer support

Everything You Need to Know!

Frequently Asked Questions

A sterile, sealed vial containing a defined amount of lyophilized peptide, labeled with product name and lot number.

Yes. A COA is available for every lot and can be requested from our support team.

Each batch is analyzed using established methods (e.g. HPLC, MS) to confirm identity and purity as stated on the COA.

Store unopened vials in a refrigerator (2–8 °C), protected from light and moisture, unless otherwise indicated on the product label.

No. All MB1 Labs products are supplied strictly as laboratory reagents for research use only and are not intended for human or veterinary use, diagnostics, or therapy.


  • Third-party tested

    Independent analytical testing to verify identity and purity of each batch.

  • COAs FOR EVERY LOT

    Comprehensive Certificates of Analysis available for all released batches.

  • RESEARCH-ONLY USE

    Supplied strictly as laboratory reagents – not for human or veterinary use.

  • CONTROLLED HANDLING

    Standardized storage and handling to help preserve compound integrity.